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Milan is located between the Po River, the Alps and Italian lakes region. The concentric layout of the city center has been influenced by the Navigli, an ancient system of navigable and interconnected canals, now mostly covered. There are only few remains of the ancient Roman colony of Mediolanum. Following the edict of Milan in 313 A.D., several basilicas were built by the city gates, still standing and refurbished over the centuries.